The Science
INTRODUCING
Regenerative Science
Immupure® is built on regenerative science to support the skin’s natural renewal processes. At the core is proline-rich polypeptide colostrum, supported by a network of bioactive compounds — including peptides, growth factors, exosomes, essential amino acids, B-complex vitamins, and minerals — that work together to reinforce the skin’s structural matrix and drive regenerative signaling.
Proline-Rich Polypeptide Colostrum
Liquid bovine colostrum forms the biological foundation of Immupure. It contains a concentrated spectrum of bioactive factors that support collagen and elastin production, promote cellular renewal, and reinforce dermal structure.
Skin Nutrition Information
Minerals
Immupure contains a balanced spectrum of minerals that act as essential cofactors in numerous cellular processes within the skin, supporting optimal cellular function.
The minerals present in Immupure include sodium, calcium, potassium, magnesium, zinc, and phosphorus.
Amino acids are considered the "building blocks" of proteins, the complex molecules present in all living organisms.
All 20 amino acids have been identified, with some recognized as "essential amino acids" because the body cannot synthesize them.
The 8 essential amino acids are Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, and Valine.
Taurine, a special amino acid, plays a crucial role in skin hydration and is known for its energizing properties.
... Read more1. Vitamin B1 (Thiamine): A coenzyme utilized in energy metabolism, it acts as an antioxidant, protecting the body from the outward signs of aging.
2. Vitamin B2 (Riboflavin): Necessary for cell respiration and growth, it facilitates the use of oxygen by the skin tissues and possesses antioxidant qualities.
3. Vitamin B3 (Nicotinamide): Required for proper blood circulation.
4. Vitamin B5 (Pantothenic Acid): An essential component in the production of coenzyme A, a vital catalyst needed for the conversion of carbohydrates, fats, and proteins into energy.
5. Vitamin B6 (Pyridoxine): Required for the synthesis of nucleic acids RNA and DNA, playing a key role in cell reproduction and cellular growth.
6. Vitamin B9 (Folic Acid): Necessary for the production of red blood cells and the synthesis of RNA and DNA. It aids in tissue growth and cell function, being crucial for the production and maintenance of new cells.
7. Vitamin B12 (Cobalamin): Aids in cell formation and cellular longevity, considered to play a significant role as an anti-aging nutrient.
... Read more
In Vivo Test Results
In a 56-day in vivo study involving twice daily application of Immupure creams, significant improvements were observed in fine lines, wrinkles, skin tone, and skin tightening.
Skin thickness increased by up to 400%, and collagen production increased by up to 210%.
The study was conducted using a 3% colostrum concentration; Immupure’s skincare collection includes formulations with concentrations of up to 15%.
In vivo test: Skin Thickness (improvement in µm)
Placebo (Blue), Immupure (Yellow)
Measurement of the influence of Immupure on skin thickness. Skin thickness was strongly improved compared to the control. (by Ultrasound - DERMASCAN)
In vivo test: Skin Tightening & Tone (Improvement in [%])
Placebo (Gray), Immupure (Blue)
Measurement of the influence of Immupure on skin tone and tightening. The skin tightening (+22%) and tonicity (+26%) as well as the skin thickness, were strongly improved compared to the control. (by Laser Profilometry)
In vivo test: Anti-Wrinkle Effect (Decrease of wrinkles [%])
Control (Gray), Placebo (Blue), Immupure (Turquoise)
Measurement of the anti-wrinkle effect. The maximum depth and volume of wrinkles were measured. The volume of wrinkles decreased by 800% compared to placebo. (by Laser Profilometry)
In vitro test Results: Collagen-I Synthesis
Immupure (Red)
The efficacy of Immupure in stimulating collagen-I synthesis was demonstrated in an in vitro test on human fibroblasts. A 1% concentration resulted in collagen-I synthesis of 210% compared to TGF-beta.
Case Study
Colostrum is produced in the mammary glands of female mammals during late pregnancy and in the first days after giving birth. It contains a high concentration of essential components present in their naturally most concentrated form during the initial 72 hours after giving birth. The composition of colostrum includes an optimal balance of vitamins, trace elements, amino acids, immunoglobulins, and growth factors.
International studies demonstrate that the components of colostrum promote and support healthy skin. The subsequent case study illustrates the positive effects of colostrum skin cream in soothing skin irritation and supporting collagen synthesis and skin regeneration.
Colostrum cannot be used in its raw state due to its high fat content, large molecular proteins, and other undesirable substances. Through newly developed, gentle biophysical production methods, fat, casein, albumin, and other contaminants are removed while the active substances remain in their natural balance.
Immupure skin cream from the original German manufacturer for Immupure LLC was used for the pilot study, with processing conducted in compliance with GMP, DIN ISO 9001, and HACCP regulations.
The case study involved 50 patients:
• 15 suffered from psoriasis
• 20 suffered from neurodermatitis
• 15 suffered from acne vulgaris
The observation period lasted 8 weeks and took place in various doctors’ offices. All patients had undergone previous dermatological treatments, yet their complaints persisted. Results were evaluated both subjectively and objectively and categorized as no improvement, slight improvement, significant improvement, or complete healing.
Seven patients initially experienced irritation and discontinued use of Immupure cream after two days, resuming after four days. Final evaluations were compiled and recorded after 8 weeks, with all other treatments discontinued during the study period. Patients applied Immupure cream to the affected areas in the morning and evening.
The case study comprised 50 patients recruited from various doctors' offices, focusing on individuals with psoriasis, neurodermatitis, and acne vulgaris that had not responded to standard treatments. The results were compiled over an 8-week period.
In all tested conditions, there was significant improvement, with every patient experiencing some level of benefit from the colostrum, ranging from slight to substantial improvement. Notably, all three test criteria exhibited noticeable, significant improvement, and there were instances of complete healing, especially among acne patients.
The efficacy of the cream can be attributed to its natural active substances system, including growth factors, amino acids, immunoglobulins, and other antibacterial substances. It can be inferred that the number of patients achieving complete healing could increase with continued treatment. Further results can be assessed after 3 months, although making statements about faster healing effects over an extended period is currently not possible.
In the case of allergen-bacterial-based skin irritations that had not responded to standard treatments, the application of Immupure colostrum resulted in significant improvement within 8 weeks.
Moreover, additional positive effects were observed for injuries such as cuts, abrasions, and burns, with these wounds healing in one-third of the time it would typically take.
Case Study Test Results (Patients)
Psoriasis (Gray), Neurodermitis (Blue), Acne (Turquoise)
Test criteria were psoriasis, neurodermatitis, and acne vulgaris, which had not been healed by standard treatments. The results were compiled over a period of 8 weeks following application of Immupure cream.